Jeffrey D Kerby Selected Research

HBOC 201 (Hemopure)

8/2009	Sodium nitrite therapy attenuates the hypertensive effects of HBOC-201 via nitrite reduction.
6/2007	Resuscitation from hemorrhagic shock with HBOC-201 in the setting of traumatic brain injury.
1/2006	Bovine hemoglobin-based oxygen-carrying solution (HBOC-201) improves flap survival in a rat model of epigastric flap failure.
8/2005	Prolonged low-volume resuscitation with HBOC-201 in a large-animal survival model of controlled hemorrhage.
11/2004	Resuscitation with a blood substitute causes vasoconstriction without nitric oxide scavenging in a model of arterial hemorrhage.
11/2003	Low-volume resuscitation with a polymerized bovine hemoglobin-based oxygen-carrying solution (HBOC-201) provides adequate tissue oxygenation for survival in a porcine model of controlled hemorrhage.
10/2003	A comparison of the hemoglobin-based oxygen carrier HBOC-201 to other low-volume resuscitation fluids in a model of controlled hemorrhagic shock.

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Jeffrey D Kerby Research Topics

Disease

35	Wounds and Injuries (Trauma) 03/2022 - 10/2003
9	Hemorrhage 01/2020 - 11/2003
8	Shock 02/2022 - 08/2005
8	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2016 - 06/2007
7	Hemorrhagic Shock 12/2020 - 10/2003
4	Pneumonia (Pneumonitis) 01/2020 - 07/2009
4	Burns 10/2018 - 07/2006
3	Hypotension (Low Blood Pressure) 02/2015 - 08/2005
2	Craniocerebral Trauma (Head Injury) 03/2022 - 06/2007
2	Exsanguination 02/2022 - 04/2016
2	Renal Insufficiency (Renal Failure) 01/2020 - 04/2015
2	Diabetes Mellitus 01/2020 - 08/2015
2	Bacterial Infections (Bacterial Infection) 11/2019 - 01/2018
2	Infections 01/2018 - 01/2017
2	Critical Illness (Critically Ill) 01/2017 - 10/2016
2	Ventilator-Associated Pneumonia 01/2017 - 05/2016
2	Inflammation (Inflammations) 10/2016 - 04/2016
2	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2016 - 07/2013
2	Sepsis (Septicemia) 12/2005 - 12/2005
2	Thrombosis (Thrombus) 02/2003 - 05/2002
1	Stroke (Strokes) 01/2022
1	Nonpenetrating Wounds 12/2020
1	Urinary Tract Infections (Urinary Tract Infection) 01/2020
1	Heart Arrest (Cardiac Arrest) 01/2020
1	Empyema 01/2019
1	Hemothorax 01/2019
1	Pneumothorax 01/2019
1	Hemolysis 01/2018
1	Lung Injury 01/2018
1	Healthcare-Associated Pneumonia 01/2017
1	Fever (Fevers) 01/2017
1	Pulmonary Edema 01/2017
1	Spinal Cord Injuries (Spinal Cord Injury) 05/2016
1	Respiratory Insufficiency (Respiratory Failure) 01/2016
1	Acute Lung Injury 08/2015
1	Inguinal Hernia (Direct Inguinal Hernia) 08/2014
1	Hypothermia 06/2014
1	Acidosis 06/2014
1	Multiple Organ Failure (MODS) 07/2013
1	Brain Edema (Cerebral Edema) 10/2010
1	Ischemia 11/2009

Drug/Important Bio-Agent (IBA)

8	Oxygen (Dioxygen)IBA 03/2012 - 10/2003
7	Hemoglobins (Hemoglobin)IBA 01/2020 - 10/2003
7	HBOC 201 (Hemopure)IBA 08/2009 - 10/2003
4	NitritesIBA 08/2015 - 01/2006
3	Angiopoietin-2IBA 03/2022 - 01/2019
3	Heme (Haem)IBA 11/2019 - 10/2016
3	Lactic Acid (Lactate)FDA LinkGeneric 01/2016 - 05/2010
3	Glucose (Dextrose)FDA LinkGeneric 08/2015 - 09/2012
3	Ringer's LactateIBA 08/2009 - 08/2005
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 08/2005 - 05/2002
2	AngiopoietinsIBA 12/2020 - 01/2019
2	ORALIT (ORS)IBA 05/2016 - 10/2008
2	Crystalloid SolutionsIBA 04/2015 - 08/2005
2	Dextrans (Dextran)FDA Link 10/2010 - 02/2008
2	SolutionsIBA 01/2006 - 11/2003
1	fibrin fragment D (D-dimer)IBA 03/2022
1	ThrombomodulinIBA 03/2022
1	Biomarkers (Surrogate Marker)IBA 03/2022
1	Hyaluronic Acid (Hyaluronan)IBA 01/2022
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2022
1	Angiopoietin-1IBA 12/2020
1	Syndecan-1 (Syndecan 1)IBA 01/2019
1	Indicators and Reagents (Reagents)IBA 01/2019
1	HMGB1 Protein (HMG1)IBA 01/2018
1	Toll-Like Receptor 4IBA 01/2018
1	Histones (Histone)IBA 01/2018
1	DNA (Deoxyribonucleic Acid)IBA 01/2018
1	HemopexinIBA 01/2018
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2017
1	Tranexamic Acid (AMCA)FDA Link 01/2016
1	Proteins (Proteins, Gene)FDA Link 08/2015
1	Blood Coagulation Factors (Coagulation Factor)IBA 06/2014
1	Protein CIBA 06/2014
1	AnticoagulantsIBA 06/2014
1	Saline SolutionIBA 10/2010

Therapy/Procedure

21	Resuscitation 03/2020 - 10/2003
7	Therapeutics 03/2020 - 12/2005
4	Erythrocyte Transfusion 11/2019 - 03/2012
3	Laparotomy 01/2022 - 11/2009
3	Mechanical Ventilators (Ventilator) 01/2017 - 07/2009
2	Palliative Care (Palliative Therapy) 08/2019 - 10/2018
2	Artificial Respiration (Mechanical Ventilation) 01/2017 - 10/2008
2	Length of Stay 05/2016 - 06/2014
2	Lasers (Laser) 06/2007 - 02/2005
1	Tourniquets 02/2022
1	Blood Transfusion (Blood Transfusions) 03/2020
1	Cardiopulmonary Resuscitation (CPR) 01/2020
1	Glycemic Control 01/2020
1	Advanced Trauma Life Support Care 01/2019
1	Thoracotomy 01/2019
1	Chest Tubes (Chest Tube) 01/2019
1	Hospital Equipment and Supplies (Supplies, Hospital) 01/2017
1	Tracheostomy 01/2017
1	Immunomodulation 04/2016
1	Extracorporeal Membrane Oxygenation 01/2016
1	Catheters 08/2014
1	Hemodilution 06/2014
1	Airway Management 04/2011
1	Colostomy 11/2009